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You are a member of a team of 2-3 specialists (we have several teams in group);
Laboratory and conceptual work around protein production in bacteria and protein purification from different sources (cell media, plasma, cell lysates);
Coordination of tasks assigned by your leader;
Collaboration with other teams and groups in the company;
Contribute towards developing molecules from early-stage discovery to lead candidate nomination;
Conceptualize experimentation around drug candidate development spanning PK, PD, and toxicological assessment in relevant animal models;
Conceptualize, develop, and execute the assays e.g., Taqman assay, Biomarker selections, IHC and flow cytometry-based assays for advancing lead molecules;
Work closely with protein, antibody, and cell biology group to ensure quantity, quality and deliverables are met;
Plan and implement data collection and analysis in support of assay protocol;
Mentoring of the day-to-day activities of colleagues specifically engaged in the carrying out of research protocol in accordance with specified program objectives;
Monitor the progress of research activities; developing and maintaining records;
work on the discovery of new antibodies using phage display technology;
analyse sequences of the identified hits with bioinformatic tools (sequencing quality evaluation, multi-sequence alignments, analysis of Sanger, and NGS data);
develop and validate new assays to extend the Pure Biologics technology platform;
run assays to support the antibody discovery and early validation programs at Pure Biologics; ELISA, cell-based binding assays, flow cytometry, plate-based functional assays;
analyse your own data and keep detailed record of all scientific experiments in electronic lab-book (in English);
regularly communicate your experimental progress to the coordinator of your research team and to the co-operating teams during meetings;
manage multiple tasks with overlapping deadlines simultaneously;
maintain databanks and storage of samples and reagents, including the collection of antibodies;
participate in laboratory- and instruments upkeeping
In this role, you are responsible for coordinating preparation, modification and formulation of proteins on different levels of drug development pipeline. The position requires leadership skills combined with a technical approach. We strongly believe in teamwork
You lead one team of 2-3 specialists (we have several teams in group)
Laboratory and conceptual work around protein production in bacteria and protein purification from different sources (cell media, plasma, cell lysates)
Contact point for planning of protein production activities
Cooperation with other teams and groups in the company
Identifying and analysing bottlenecks, quality and yield
Coaching and supporting your team members
Coordinating improvement activities in your department
In this role, you are involved in preparation, modification and formulation of proteins on different levels of drug development pipeline. The position requires technical and planning skills. We strongly believe in teamwork
You are a member of a team of 2-3 specialists (we have several teams in group)
Laboratory and conceptual work around protein production in bacteria and protein purification from different sources (cell media, plasma, cell lysates)
Coordination of tasks assigned by your leader
Collaboration with other teams and groups in the company
Research Team Coordinator (Mammalian Protein Expression)
Duńska 11, Fabryczna, Wrocław
Wygasła: 22.04.2022
full-time
umowa o pracę
full office work
manager / supervisor
Obowiązki:
In this role, you are responsible for coordinating the production of proteins in mammalian cell lines for drug development at different stages. The position requires leadership skills combined with a technical approach. This empowers you to correctly anticipate needs and further develop with organization
You lead a team of 3-4 specialists
Laboratory and conceptual work around protein expression in mammalian systems (antibodies and their fragments, receptor fragments and other types of recombinant proteins and their parts)
Main point of contact for planning of all protein expression activities
Cooperation with protein purification teams
Identifying and analysing bottlenecks, quality and yield
Coaching and supporting your team members
Coordinating improvement activities in your department
Conducting state-of-the-art research and giving opinions about the patentability of an invention;
Performing legal status, the scope of protection and freedom to operate analyses;
Monitoring and analysis of competitive intellectual property based on regular patent survey aligned to prioritized markets and technologies;
Review of the proposed publications for impact on patentability & confidentiality issues;
Communication with patent attorneys and local government agencies regarding the intellectual property matters;
Supporting role in preparation of new patent applications for filing with the UPRP and EPO;
Assist in developing and executing IP strategy;
Proactive collaboration and developing relationship with teams and stakeholders to facilitate proper knowledge dissemination pertain IP processes and issues
Lead a project, create and monitor goals and scope, timelines, risks and mitigation plans, budget estimations;
Closely interact with all functional disciplines of the company in a matrix role, integrating all expertise into the project;
Build and develop the project team to ensure maximum performance, providing purpose, direction, and motivation;
Troubleshoot at all levels of the project;
Coordinate internal and external resources, ensuring projects remain within scope, schedule, and defined budgets, in collaboration with project team members from various functional departments;
Analyse project progress and, when necessary, adapt scope, timelines, and costs to ensure that project team adheres to project requirements;
Ensure optimization of project/program resources (capital, effort, organization, departments, and systems), time, cost and quality;
Establish and maintain relationships with third parties (subcontractors, consultants) and all project stakeholders, providing day-to-day contact on project status and changes;
Communicate properly and in time to all project stakeholders; reports and escalates to management if needed
Utrzymywać i rozbudowywać infrastrukturę IT nowoczesnej firmy biotechnologicznej:
• jako pierwsza linia wsparcia użytkowników w zakresie obsługi stacji roboczych, laptopów, telefonów komórkowych, drukarek sieciowych, sieci LAN;
• wykonując instalacje i konserwacje stacji roboczych i urządzeń peryferyjnych;
• prowadząc bieżący monitoring środowiska IT;
• zapewniając wsparcie dla Zespołu IT w realizacji bieżących działań oraz projektów;
• prowadząc inwentaryzację zasobów IT;
• pomagając w utrzymaniu instalacji budynkowych takich jak kontrola dostępu, monitoring laboratoriów czy systemy awaryjnego zasilania
Będziesz również Ambasadorem narzędzi stosowanych w spółce, prowadząc szkolenia z zakresu systemu, aplikacji, możliwości wykorzystania narzędzi oraz wsparcia użytkowników (pracujemy z LabGuru, Wrike, MS365, systemem ERP, prostymi bazami danych SQL i innymi narzędziami)
Comprehensively managing a project in accordance to the project’s schedule, expectations and sponsor guidelines
Coordinating the experimental pipeline between research teams as well as external contractors to achieve project goals and milestones within set timelines
Acquiring and coordinating resources through managing project contracts, subcontractors, tenders
Collecting and synthesizing project information and data, including scientific data, effectively managing the knowledge base of the project
Reporting and presenting information and data to various stakeholders, including internal and external parties of different levels
Taking a high level of responsibility for entrusted tasks
Further developing and honing above average communication and cooperation skills in a matrix company structure
Independently and proactively driving the activities of an entrusted project
Maintaining an openness and a proactive approach with respect to knowledge sharing and results presenting
Continually developing and refining skills of data analysis and the drawing of solid evidence-based conclusions